Percutaneous left atrial appendage occlusion: the Munich consensus document on definitions, endpoints, and data collection requirements for clinical studies.
نویسندگان
چکیده
The increasing interest in left atrial appendage occlusion (LAAO) for ischaemic stroke prevention in atrial fibrillation (AF) fuels the need for more clinical data on the safety and effectiveness of this therapy. Besides an assessment of the effectiveness of the therapy in specific patients groups, comparisons with pharmacological stroke prophylaxis, surgical approaches, and other device-based therapies are warranted. This paper documents the consensus reached among clinical experts in relevant disciplines from Europe and North America, European cardiology professional societies, and representatives from the medical device industry regarding definitions for parameters and endpoints to be assessed in clinical studies. Adherence to these definitions is proposed in order to achieve a consistent approach across clinical studies on LAAO among the involved stakeholders and various clinical disciplines and thereby facilitate continued evaluation of therapeutic strategies available.
منابع مشابه
A Semi-Automated Algorithm for Segmentation of the Left Atrial Appendage Landing Zone: Application in Left Atrial Appendage Occlusion Procedures
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متن کاملPercutaneous left atrial appendage occlusion: New perspectives for the method.
Ischemic stroke is a common complication of atrial fibrillation (AF). Currently, oral anticoagulant drugs are the most commonly used method of stroke prevention. Left atrial appendage occlusion is thought to be the main source of thrombi in patients with AF. Percutaneous left atrial appendage is a valuable therapeutic option for selected high-risk patients with AF and contraindications for oral...
متن کاملSegmentation of the Left Atrial Appendage in the Echocardiographic Images of the Heart Using a Deep Neural Network
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متن کاملSegmentation of the Left Atrial Appendage in the Echocardiographic Images of the Heart Using a Deep Neural Network
Introduction: Cardiovascular diseases are one of the leading causes of mortality in today’s industrial world. Occlusion of left atrial appendage (LAA) using the manufactured devices is a growing trend. The objective of this study was to develop a computer-aided diagnosis system for the identification of LAA in echocardiographic images. Method: The data used in this descriptive analytical study ...
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عنوان ژورنال:
- EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
دوره 12 1 شماره
صفحات -
تاریخ انتشار 2016